Chemical Structure
Inhibitor
2847 Citations
Gefitinib
BT-0001
Gefitinib is a potent and selective EGFR tyrosine kinase inhibitor used in the treatment of non-small cell lung cancer. It blocks signaling through the epidermal growth factor receptor in target cells.
Biological Activity
Selective EGFR tyrosine kinase inhibitor that blocks signal transduction pathways implicated in the proliferation and survival of cancer cells.
Product Specifications
CAS Number184475-35-2
Molecular FormulaC22H24ClFN4O3
Molecular Weight446.9 g/mol
TargetEGFR
PathwayEGFR/HER2 Signaling
Disease AreaCancer
IC50/EC50/KdIC50: 33 nM (EGFR)
Purity>99%
SolubilityDMSO: ≥50 mg/mL
Storage-20°C, desiccated, protected from light
SpeciesHuman
Available Sizes
| Size | Price | |
|---|---|---|
| 5 mg | $45.00 | |
| 25 mg | $150.00 | |
| 100 mg | $420.00 |