Chemical Structure
Inhibitor
4520 Citations
Rapamycin (Sirolimus)
BT-0002
Rapamycin is a specific mTOR inhibitor and immunosuppressant. It forms a complex with FKBP12 and inhibits mTORC1, blocking downstream signaling involved in cell growth and proliferation.
Biological Activity
Potent and specific mTOR inhibitor that inhibits T-cell activation and proliferation.
Product Specifications
CAS Number53123-88-9
Molecular FormulaC51H79NO13
Molecular Weight914.17 g/mol
TargetmTOR
PathwayPI3K/Akt/mTOR
Disease AreaCancer
IC50/EC50/KdIC50: 0.1 nM (mTOR)
Purity>98%
SolubilityDMSO: ≥25 mg/mL, Ethanol: ≥2 mg/mL
Storage-20°C, desiccated
SpeciesHuman, Mouse, Rat
Available Sizes
| Size | Price | |
|---|---|---|
| 1 mg | $30.00 | |
| 5 mg | $95.00 | |
| 50 mg | $580.00 |