Chemical Structure
Inhibitor
3200 Citations
Rapamycin (Sirolimus)
BT-0011
Rapamycin is a macrolide compound and allosteric inhibitor of mTOR complex 1 (mTORC1). Used as an immunosuppressant and in cancer research.
Biological Activity
Binds FKBP12 and inhibits mTORC1, suppressing protein synthesis, cell growth, and proliferation.
Product Specifications
CAS Number53123-88-9
Molecular FormulaC51H79NO13
Molecular Weight914.17 g/mol
TargetmTOR
PathwayPI3K/AKT/mTOR Signaling
Disease AreaCancer, Immunology
IC50/EC50/KdIC50: 0.1 nM (mTOR)
Purity>99%
SolubilityDMSO: ≥25 mg/mL; Ethanol: ≥25 mg/mL
Storage-20°C, desiccated
SpeciesHuman, Mouse, Rat
Available Sizes
| Size | Price | |
|---|---|---|
| 5 mg | $65.00 | |
| 25 mg | $220.00 |