Erlotinib

BT-0012

Erlotinib is a reversible EGFR tyrosine kinase inhibitor approved for non-small cell lung cancer and pancreatic cancer.

Biological Activity

Competitively inhibits EGFR autophosphorylation, blocking downstream RAS/MAPK and PI3K/AKT signaling.

Product Specifications

CAS Number183319-69-9

Molecular FormulaC22H23N3O4

Molecular Weight393.44 g/mol

TargetEGFR

PathwayEGFR Signaling

Disease AreaCancer

IC50/EC50/KdIC50: 2 nM (EGFR)

Purity>99%

SolubilityDMSO: ≥10 mg/mL

Storage-20°C, desiccated

SpeciesHuman

Available Sizes

Size	Price
10 mg	$45.00
50 mg	$160.00