Chemical Structure
Inhibitor
1560 Citations

Venetoclax

BT-0013

Venetoclax is a highly selective BCL-2 inhibitor approved for chronic lymphocytic leukemia (CLL) and acute myeloid leukemia (AML).

Biological Activity

Directly binds BCL-2 with high affinity, displacing pro-apoptotic proteins and triggering mitochondrial apoptosis.

Product Specifications
CAS Number1257044-40-8
Molecular FormulaC45H50ClN7O7S
Molecular Weight868.44 g/mol
TargetBCL-2
PathwayApoptosis
Disease AreaCancer
IC50/EC50/KdKi: <0.01 nM (BCL-2)
Purity>99%
SolubilityDMSO: ≥10 mg/mL
Storage-20°C, desiccated
SpeciesHuman
Available Sizes
SizePrice
5 mg$80.00
25 mg$280.00