Chemical Structure
Inhibitor
1100 Citations
Panobinostat
BT-0016
Panobinostat is a pan-HDAC inhibitor approved for multiple myeloma. It inhibits class I, II, and IV HDACs.
Biological Activity
Induces hyperacetylation of histones and non-histone proteins, leading to cell cycle arrest and apoptosis.
Product Specifications
CAS Number404950-80-7
Molecular FormulaC21H23N3O2
Molecular Weight349.43 g/mol
TargetHDAC
PathwayEpigenetics / HDAC
Disease AreaCancer
IC50/EC50/KdIC50: 5 nM (HDAC1), 4 nM (HDAC2)
Purity>98%
SolubilityDMSO: ≥10 mg/mL
Storage-20°C, desiccated
SpeciesHuman
Available Sizes
| Size | Price | |
|---|---|---|
| 5 mg | $55.00 | |
| 25 mg | $180.00 |